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Immune ModulatorsResearch Only · Not FDA-Approved

LL-37Human cathelicidin antimicrobial peptide

Understand the mechanism, the current regulatory status, and the evidence — then decide your next step with a clinician who knows these compounds. The information below is educational reference only.

Reviewed with a True Heal medical professional before any protocol begins.
Research Only · Not FDA-Approved. Not FDA-approved. Provided as an educational reference only — not offered or sold by True Heal Wellness. True Heal Wellness does not offer, sell, or administer LL-37; this page is provided strictly as an educational reference.
Mechanism
Disrupts microbial membranes and modulates immune, angiogenic and epithelial-repair pathways.
Researched For
Innate immunity · Biofilm research · Wound healing
The essentials

At a Glance

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Compound type

Antimicrobial peptide

Researched for

Innate immunity, biofilm research and wound healing.

Evidence level

D/E — Preclinical to experimental human use

U.S. FDA status

Not FDA-approved.

Routes studied

Experimental.

Doses studied

Research write-ups list research dosing, but there is no FDA-approved or evidence-based routine human regimen.

Safety notes

Exogenous dosing could provoke inflammatory or immune effects; human safety is not established.

Anti-doping (WADA)

Unknown.

Availability at True Heal

True Heal Wellness does not offer, sell or administer LL-37. This page exists as an educational reference only.

Last reviewed

2026-08-11

Regulatory status

Not FDA-approved.

LL-37 is not a treatment for Lyme disease, MRSA or chronic infection.

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What LL-37 is

Human cathelicidin antimicrobial peptide studied in innate immunity, infection biology, inflammation and wound healing. It is also referred to as Cathelicidin LL-37.

How it works

Disrupts microbial membranes and modulates immune, angiogenic and epithelial-repair pathways.

What the evidence shows

Strong basic science; insufficient evidence for routine therapeutic administration.

Evidence level: D/E — Preclinical to experimental human use.

Routes studied: Experimental.

Doses studied: Research write-ups list research dosing, but there is no FDA-approved or evidence-based routine human regimen.

What this page does not claim

LL-37 is not a treatment for Lyme disease, MRSA or chronic infection.

Safety considerations

Exogenous dosing could provoke inflammatory or immune effects; human safety is not established.

  • Cautions and contraindications: Autoimmune/inflammatory context requires caution.
  • Possible interactions: Immunomodulators.

Sport and anti-doping

Unknown.

Availability at True Heal Wellness

True Heal Wellness does not offer, sell or administer LL-37. This page exists as an educational reference only.

Straight answers

Frequently asked

What is LL-37?

Human cathelicidin antimicrobial peptide studied in innate immunity, infection biology, inflammation and wound healing.

Is LL-37 FDA-approved?

Not FDA-approved. LL-37 is not a treatment for Lyme disease, MRSA or chronic infection.

What is LL-37 researched for?

Innate immunity, biofilm research and wound healing.

What does the evidence on LL-37 show?

Strong basic science; insufficient evidence for routine therapeutic administration. Evidence level: D/E — Preclinical to experimental human use.

What are the safety considerations with LL-37?

Exogenous dosing could provoke inflammatory or immune effects; human safety is not established. Cautions: Autoimmune/inflammatory context requires caution.

Does True Heal Wellness offer LL-37?

True Heal Wellness does not offer, sell or administer LL-37. This page exists as an educational reference only.

The evidence

References

  1. PepEd Hub — LL-37 compound profile. pepedhub.com
Your next step

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Medical disclaimer. For research and educational purposes only. This content does not constitute medical advice — consult a qualified healthcare provider before beginning any protocol.

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