What Orexin A is
Endogenous hypothalamic neuropeptide central to wakefulness, arousal and appetite regulation. It is also referred to as Hypocretin-1.
How it works
Activates orexin receptors OX1R/OX2R involved in arousal and energy-balance circuits.
What the evidence shows
Orexin biology is well established, but direct Orexin-A peptide therapy is not an FDA-approved clinical treatment.
Evidence level: D/E — Experimental therapeutic evidence.
Routes studied: Experimental/intranasal research.
Doses studied: No established FDA-approved peptide dose.
What this page does not claim
Approved orexin-receptor drugs are a different thing from the Orexin-A peptide itself.
Safety considerations
Direct peptide administration safety is not established.
- Cautions and contraindications: Sleep/cardiovascular disorders require specialist review.
- Possible interactions: CNS stimulants/sedatives may interact at a systems level.
Sport and anti-doping
Unknown.
Availability at True Heal Wellness
True Heal Wellness does not offer, sell or administer Orexin A. This page exists as an educational reference only.